Trials

University Hospitals Birmingham NHS Foundation Trust is a regional and national centre for specialist clinical services.

It is home to some of the country’s leading clinical research institutions, and is dedicated to developing and implementing groundbreaking treatments, technologies and techniques.

  • Organising Improvement: Regulating Patient Safety from Blunt to Sharp End

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  • The possible clinical significance of oligodendroglioma cells in glioblastoma multiforme

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  • DESTINY

    A trial of de-escalation and stopping treatment in chronic myeloid leukaemia patients with excellent responses to tyrosine kinase inhibitor therapy (De- Escalation and Stopping Treatment of Imatinib Nilotinib or sprYcel in chronic myeloid leukaemia) (DESTINY)

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  • Oral Azacitidine (CC-486)

    A phase 1/2 dose and schedule finding study to evaluate the safety tolerability pharmacokinetics and preliminary efficacy of oral Azacitidine (cc486) in subjects with acute Myeloid Leukemia or Myelodysplastic syndromes after Allogeneic Hematopoietic stem cell Transplantation

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  • PANTS

    Investigation of the clinical serological and genetic factors that determine primary non-response loss of response and adverse drug reactions to Anti-TNF drugs in patients with active luminal Crohn’s Disease.

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  • ASPIRE

    A trial aimed at enhancing immunity to Influenza in elderly individuals through reversal of immune senescence mediated by herpes virus infection

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  • Studies on regulation of thyroid cell growth and function

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  • Does altering the activity of receptors for the active metabolite of vitamin A (all-trans retinoic acid) allow human adult blood cells to expand ex vivo?

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  • A multi centre double blind double dummy randomised positive controlled study comparing the efficacy and safety of Lacosamide (200 to 600mg/day) to controlled release Carbamazepine (400 to 1200mg/day) used as Monotherapy in subjects (=16 years) newly or recently diagnosed with Epilepsy and experiencing partial onset or generalised Tonic Clonic Seizures

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  • Cogwatch

    Cognitive Rehabilitation of Apraxia and Action Disorganisation Syndrome

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