Oncology Trials

  • 16/11/2025

    The role and mechanism of action of myeloid-derived suppressor cells (MDSCs) in malignancies

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  • 31/01/2021

    FOCUS4

    FOCUS4 – Molecular selection of therapy in colorectal cancer: a molecularly stratified randomised controlled trials programme

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  • 31/12/2020

    Characterising the immune profile and microenvironment of solid tumours and investigating how these features correlate with clinical prognosis and response to treatment

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  • 26/10/2019

    CHECKMATE 227

    An OpenLabel Randomized Phase 3 Trial of Nivolumab or Nivolumab plus Ipilimumab versus platinum doublet chemotherapy in Subjects with ChemotherapyNaïve Stage IV or Recurrent NonSmall Cell Lung Cancer (NSCLC)

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  • 31/12/2024

    IMPOWER

    GO40241: A PHASE III DOUBLE-BLINDED MULTICENTER RANDOMIZED STUDY EVALUATING THE EFFICACY AND SAFETY OF NEOADJUVANT TREATMENT WITH ATEZOLIZUMAB OR PLACEBO IN COMBINATION WITH PLATINUM-BASED CHEMOTHERAPY IN PATIENTS WITH RESECTABLE STAGE II IIIA OR SELECT IIIB NON-SMALL CELL LUNG CANCER

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  • 31/12/2022

    MERU

    A Randomized Double-Blind Placebo-Controlled Phase 3 Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Subjects with Extensive Stage Small Cell Lung Cancer (MERU)

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  • 30/09/2018

    Lung MATRIX

    Multi-drug genetic marker-directed non-comparative multi-arm Phase II trial in Non-Small Cell Lung Cancer

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  • 31/12/2023

    An Open-Label Multi-Centre Phase I/IIa Study Evaluating the Safety and Clinical Activity of Neoantigen Reactive T cells in Patients with Advanced Non-Small Cell Lung Cancer (CHIRON)

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  • 18/12/2026

    Safety and Tolerability of AGI-134

    A phase I/IIa multicentre open label study designed to evaluate the safety and tolerability of AGI-134 as monotherapy and in combination with pembrolizumab in unresectable metastatic solid tumours

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  • 30/09/2022

    MARS 2

    Mesothelioma and Radical Surgery 2: a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decortication for patients with malignant pleural mesothelioma

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