UHB top recruiter to national trial

18 April 2019

The Queen Elizabeth Hospital Birmingham (QEHB) is one of the leading recruiters to a national trial that could improve mortality rates for people having emergency bowel surgery.

The Fluid Optimisation in Emergency Laparotomy (FLO-ELA) trial, which started in 2017, is aiming to recruit 8000 patients, and is the largest trial of its kind in the UK.

Led by Dr Rajneesh Sachdeva, consultant anaesthetist, the team at QEHB have recruited more than 50 patients to the trial, which is intended to finish recruitment in 2020.

The trial will use a heart blood flow monitor to guide the amount of fluid given to patients during and after surgery.

This new technique will be compared with the current standard care, to investigate if using the monitor to guide the dose and timing of fluid given helps to reduce mortality rates.

“The FLO-ELA trial has the potential to lead to significantly improved outcomes for emergency bowel surgery,” said Rajneesh.

“As one of 50 hospitals recruiting participants to the trial, it’s a real honour to be involved in something that could benefit a large number of people in the future.

“I’d like to thank everyone who’s taken part so far at QEHB, as well as all my colleagues who have helped with recruitment into the trial, with particular thanks to other anaesthetic registrars and the emergency theatre team.”

Joanne Plumb, Deputy Director of Research Development and Innovation, added: “Clinical trials like FLO-ELA have the potential to transform patient care, and are a crucial part of the service UHB provides for our patients to improve their care.

“Rajneesh and his colleagues deserve to be recognised and congratulated for their hard work in recruiting patients to the trial as one of the top recruiting hospitals.”

At QEHB, the trial involves a team of research nurses working alongside colleagues in critical care, surgery and anaesthesia.

The FLO-ELA trial is funded by the National Institute for Health Research Health Technology Assessment Programme, and is sponsored by University Hospital Southampton NHS Foundation Trust.