Trials

University Hospitals Birmingham NHS Foundation Trust is a regional and national centre for specialist clinical services.

It is home to some of the country’s leading clinical research institutions, and is dedicated to developing and implementing groundbreaking treatments, technologies and techniques.

  • EUROBACT II

    Epidemiology and determinant of outcomes of hospital acquired Blood Stream Infections in the intensive care. (Eurobact II)

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  • ProEuroDILI Registry Version 1

    Prospective European DILI registry: Creation of a multicentre and multidisciplinary European registry of prospective drug-induced liver injury cases

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  • A Multicenter Randomized Double-Blind Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Elafibranor at doses of 80 mg and 120mg After 12 Weeks of Treatment in Patients With Primary Biliary Cholangitis and Inadequate Response to Ursodeoxycholic Acid

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  • MERLIN

    An adaptive single arm multi-centre phase Iia clinical trial investigating the safety and activity of the use of a single infusion of sorted Mesenchymal Stromal Cells to reduce liver inflammation in the treatment of patients with primary sclerosing cholangitis and autoimmune hepatitis

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  • Development of Imaging Techniques for MRI Scanners to improve disease diagnosis and monitoring

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  • A Phase 2 Dose Ranging Randomized Double Blind Placebo Controlled Study Evaluating the Safety Tolerability Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary Cholangitis (PBC) With Or Without An Inadequate Response To Ursodeoxycholic Acid (UDCA)

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  • UK PBC Genetics Study

    Investigation of the genetic and molecular pathogenesis of primary biliary cirrhosis

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  • A Double-Blind Randomized Placebo-Controlled Clinical Trial to Assess the Efficacy and Safety of Oral GKT137831 in Patients with Primary Biliary Cholangitis Receiving Ursodeoxycholic Acid and with Persistently Elevated Alkaline Phosphatase

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  • NUC-5

    Double-blind randomized placebo-controlled phase III study comparing norursodeoxycholic acid capsules with placebo in the treatment of primary sclerosing cholangitis

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  • GLIMMER

    A randomized double-blind multi-dose placebo-controlled study to evaluate the efficacy safety and tolerability of GSK2330672 administration for the treatment of pruritus in patients with primary biliary cholangitis

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