Trials

University Hospitals Birmingham NHS Foundation Trust is a regional and national centre for specialist clinical services.

It is home to some of the country’s leading clinical research institutions, and is dedicated to developing and implementing groundbreaking treatments, technologies and techniques.

  • ELF

    Emergency Laparotomy and Frailty- a national multi-centre study of frail older surgical patients undergoing emergency

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  • Inflammation in Ocular Surface Disease

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  • Monocyte and macrophage phenotype and function in sepsis acute hepatic failure and chronic liver disease.

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  • PRISM

    Prevention of Respiratory Insufficiency after Surgical Management (PRISM) Trial: A pragmatic randomised controlled trial of continuous positive airway pressure (CPAP) to prevent respiratory complications and improve survival following major abdominal surgery

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  • FLO-ELA trial

    Open multicentre randomised controlled trial of cardiac output-guided haemodynamic therapy compared to usual care in patients undergoing emergency bowel surgery.

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  • Evaluating the subjective and objective performance of instrumentation used and intraocular devices implanted during routine ocular surgery

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  • EXCELLENT

    A multicentric controlled phase I / Iib study evaluating the safety and the efficacy of in vitro expanded peripheral blood CD34+ stem cells output by the StemXpand® Automated Process and injected in patients with an acute myocardial infarction and a LVEF remaining below or equal to 45% after PTCA and stent(s) implantation versus standard of care

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  • Aegis II

    A Phase 3 Multicenter Double-blind Randomized Placebo-controlled Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects with Acute Coronary Syndrome

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  • TREATT

    TREATT: Trial to EvaluAte Tranexamic acid therapy in Thrombocytopenia: A double blind randomised controlled trial evaluating the safety and efficacy of Tranexamic acid in patients with haematological malignancies with severe thrombocytopenia

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  • RapidNSTEMI

    A randomised controlled trial of very early angiography +/- intervention versus standard of care on outcomes in patients with non ST-elevation myocardial infarction.

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