Trials

University Hospitals Birmingham NHS Foundation Trust is a regional and national centre for specialist clinical services.

It is home to some of the country’s leading clinical research institutions, and is dedicated to developing and implementing groundbreaking treatments, technologies and techniques.

  • Monocyte and macrophage phenotype and function in sepsis acute hepatic failure and chronic liver disease.

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  • EXCELLENT

    A multicentric controlled phase I / Iib study evaluating the safety and the efficacy of in vitro expanded peripheral blood CD34+ stem cells output by the StemXpand® Automated Process and injected in patients with an acute myocardial infarction and a LVEF remaining below or equal to 45% after PTCA and stent(s) implantation versus standard of care

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  • GaPP2

    A multi-centre double blind randomised controlled trial of the efficacy and mechanism of action of gabapentin for the management of chronic pelvic pain in women

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  • Inflammation in Ocular Surface Disease

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  • PRISM

    Prevention of Respiratory Insufficiency after Surgical Management (PRISM) Trial: A pragmatic randomised controlled trial of continuous positive airway pressure (CPAP) to prevent respiratory complications and improve survival following major abdominal surgery

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  • A Phase Ib/ii Study Evaluating the Safety and Efficacy of Obinutuzumab in Combination With Polatuzumab Vedotin and Lenalidomide in Patients With Relapsed Or Refractory Follicular Or Diffuse Large B-cell Lymphoma

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  • Evaluating the subjective and objective performance of instrumentation used and intraocular devices implanted during routine ocular surgery

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  • COS-B

    Optimising evidence-based decision-making for patients with Burns by the development of a Core Outcome Set and the identification of outcome measurement tools (COSB).

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  • FLO-ELA trial

    Open multicentre randomised controlled trial of cardiac output-guided haemodynamic therapy compared to usual care in patients undergoing emergency bowel surgery.

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  • RapidNSTEMI

    A randomised controlled trial of very early angiography +/- intervention versus standard of care on outcomes in patients with non ST-elevation myocardial infarction.

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