ReferenceRRK4096

EVALUATING THE NET EFFECTS OF EXTENDING THE AGE RANGE FOR BREAST SCREENING IN THE NHS BREAST SCREENING PROGRAMME IN ENGLAND FROM 50-70 YEARS TO 47-73 YEARS

Research Summary

Currently all women aged 50-70are invited for breast screening every three years. In 2007 the Cancer Reform Strategyannounced that from 2012 the NHS Breast Screening Programme (NHSBSP) would cover women aged 47-73.Ascapacity does not allow for full immediate roll out across the whole of England this age extension is being phasedinwith full coverage intended from 2012 although this may now be delayed due to slower than expected introduction ofdigital mammography.To date there is limited evidence on the net benefit of extending (up or down) the age range for breast screening; notrial has looked at the added value of one extra screen within an existing screening programme.This study proposes randomising the phasinginof the age extension and collecting information on breast cancer incidence and mortality over the following 10 years. This would provide unbiased evidence on the net effects ofextending the age range for breast screening. The findings have the potential to inform future screening policy in theUK and elsewhere. If the study is not carried out this unique opportunity of establishing the net benefit of adding anextra early and extra late screen to an existing screening programme will be missed.All Breast Screening Units in England will participate in the study with the exception of a few using a nonstandardmethod to invite women for screening.The age extension is funded by central government and will proceed regardless of whether our study goes ahead ornot and therefore regardless of whether the phasinginis randomised or not. Followupof study members for breastcancer incidence and mortality will be funded by the NHSBSP.

Research Overview
Sponsor University of Oxford
Project Status Open
Proposed End Date 28/02/2019
Study Run through CRF? No
Recruitment so far 0